Cuauhtemoc Blanco gets his first start for the injured Carlos Vela and Andres Guardado comes in for the suspended Efrain Juaez.
Blanco, former Chicago Fire player has the wiles but does he have the staying power?
Mexico: 1-Oscar Perez; 5-Ricardo Osorio, 15-Hector Moreno, 2-Francisco Rodriguez, 3-Carlos Salcido, 18-Andres Guardado, 4-Rafael Marquez, 6-Gerardo Torrado, 17-Giovani Dos Santos, 9-Guillermo Franco, 10-Cuauhtemoc Blanco.
Uruguay: 1-Fernando Muslera; 2-Diego Lugano, 6-Mauricio Victorino, 4-Jorge Fucile, 16-Maximiliano Pereira, 15-Diego Perez, 17-Egidio Arevalo, 7-Edinson Cavani, 11-Alvaro Pereira, 9-Luis Suarez, 10-Diego Forlan.
Referee: Viktor Kassai (Hungary)